Nilanjan

Nilanjan Chatterjee, PhD

Bloomberg Distinguished Professor

Department of Biostatistics, Bloomberg School of Public Health Department of Oncology, School of Medicine

Johns Hopkins University

Contact:
Johns Hopkins Bloomberg School of Public Health
Department of Biostatistics
615 N Wolfe Street
Baltimore, MD 21205
Phone: 410-502-8971
Fax: 410-955-0958
E-Mail: nilanjan@jhu.edu
Administrative Coordinator:
Kim Clay
Phone:  410-955-3067
Email:  kphilpo3@jhmi.edu

GENESIS

DESCRIPTION

The goal of GENESIS is to analyze summary-level GWAS statistics and external linkage disequilibrium information to estimate common variants effect-size distributions, characterized by the proportion of underlying susceptibility SNPs and a flexible normal-mixture model for their effects.

DETAILS

This package allows flexibility by considering a 2- or 3-component model, which respectively incorporate a single normal, or a mixture of two normal distributions, for specifying the effects of non-null SNPs. This package also allows users to make predictions regarding yield of future GWAS with larger sample sizes.